Seriously, resveratrol is a natural component of red wine and a powerful antioxidant. It also increases insulin sensitivity. Insulin insensitivity is a crucial marker for diabetes, and is also a marker for heart disease, weight gain, obesity, cancer, and on the list goes. An ailing person who can improve their insulin sensitivity is likely to see a major shift in their health.
Meredith Hawkins, MD, professor of medicine and director of the Global Diabetes Initiative at Einstein, administered a significant dose of resveratrol to overweight adults with insulin resistance. She reportedly found a 40% increase to insulin sensitivity in muscle and fat cells, a significant improvement to glucose tolerance, but no effect on liver cells’ insulin receptivity. That’s not diabetes prevention, but it is an exciting find and a fabulous start.
Fast forward a little over a half decade. Many scientists already observed that administering resveratrol appeared to block “adipogenesis,” i.e. the formation of fat. Along come the findings of Kee-Hong Kim, researcher and assistant professor of food science at Purdue University. He looked a little closer at the process and found resveratrol converts to another substance called piceatannol when in the body.
Before becoming official mature fat or “adipose” cells, potential lipids loiter for about 10 days as “pre” adipocytes. These pre adipocytes are just waiting for insulin to come along and bind to the insulin receptor on their outer surface, propelling them forth into the fat storage process (“adipo-genesis”).
Not if piceatannol can help it. Piceattanol has the curious habit of pretending to be insulin and getting away with it! The chemical compound will march right up to the baby wanna-be fat cells and bind to their insulin receptor, thus blocking insulin from interacting with the preadipocytes. As Kim said, “In the presence of piceatannol, you can see delay or complete inhibition of adipogenesis.”
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Article written and contributed by Francis Williams, Master Practitioner of Energy Leadership Index and avid sports enthusiast. Francis is a member of the Gay Men's Basketball League in NYC and a supporter of Out of Bounds NYC. He lives in Putnam Valley and works throughout NYC and the Hudson Valley. Francis is committed to assisting OOBNYC.org in raising $20,000 for their trip to Gay Games 2014.
